run amok
He lost it and ran amok!
Check this out: "The authors examine amok, a syndrome first described in Malaysia that consists of homicidal frenzy preceded by a state of brooding and ending with somnolence and amnesia. They discuss the concept of and criteria for a culture-specific disorder and propose that amok be classified as a culture-specific explosive behavioral disorder in DSM-IV." (wiki amok DSM-IV)
Running amok is a recognized psychopathological condition! I wonder if there's an Amok pill to make it vanish.