my own experiences
#1
Posted 27 December 2007 - 11:54 AM
#2
Posted 28 December 2007 - 03:21 AM
Brain zaps - well, actually, full body zaps that feel like a roiling wave of numbness from head to toe is my biggest complaint. I'm also feeling bad vertigo, a feeling of ... disorientation? I drive a lot at my job, and this is a real problem. Manic flashes, followed by feelings of deadness or exhaustion - also a problem at my job. Shakiness, some problems with hand-and-eye coordination. Finally, nausea; my doc told me Cymbalta slows down the digestive system, and that sucker is ramping up again. Loss of appetite.
I'm hoping this will go away within a few days, or a week at most.
My doc told me it was unsafe to take this stuff for over a year. But he failed to tell me anything about these dreadful withdrawal symptoms. If I'd have known then what I know now ...
#3
Posted 28 December 2007 - 03:34 PM
#4
Posted 31 December 2007 - 09:47 AM
I've been treated for depression for years. Last year< I found I have hypothyroidism and one of the symptoms is depression. Had my psychiatrist every tested me for thyroid problems? Nope! Found a holistic MD guiding me through withdrawing from Cymbalta-60 mg/day that I've been taking for the last 2 years. I've been dissolvong cap contents into 8 ounces of water and drinking one less ounce per week (down to 4 ounces of 30 mg.). I'm making the move to St. John's wort and 5 HTP for the time being. Depressed right now but could be the holiday season, too. I'm off work til next week and it's gloomy out.
Anyone try SJW and 5HTP?
#5
Posted 03 January 2008 - 11:37 PM
#6
Posted 04 January 2008 - 10:00 AM
#7
Posted 04 January 2008 - 11:15 PM
#8
Posted 09 January 2008 - 12:49 AM
#9
Posted 11 January 2008 - 03:26 AM
So, benedryl? How many mg per day? Does it only counteract the zaps or do something else? All info deeply appreciated. My psychopharmacologist never told me cymbalta was addictive. Great, eh? I expect to call him very soon but can't get an appointment until the end of Jan. Yuk.
:roll:
#10
Posted 11 January 2008 - 05:10 PM
I told the doc my plan was to divide the 20's into halves and repackage the halves in new capsules. Of course, there is no practical way to be exact about equally dividing those little granules. They are all different sizes in order to achieve the "sustained release" effect, but what the hey, I'm doin' the best I can. There are approx 180 granules in each 20mg cap. Instant eyestrain.
Current scheme is to stay on 10mg/day for about a week or so. The "zaps" this afternoon are greatly decreased from when on no dose at all, but I hope they disappear. I don't want to reduce to 5mg/day until then. I remember these zaps from right after I had a thalamic stroke some 4 years ago. Exactly the same effect, but that time they went away after a couple of weeks. Maybe there's some kind of connection there...
I've ordered two recommended books on safely kicking these depressing antidepressant drugs and hope my wife, who's been on Effexor, doesn't have to go through too much of the same experience.
Hope someone benefits from this feedback. Ciao.
8-)
#11
Posted 11 January 2008 - 10:52 PM
#12
Posted 12 January 2008 - 09:27 AM
Good luck, all...
8-)
#13
Posted 17 January 2008 - 12:47 AM
#14
Posted 17 January 2008 - 10:10 AM
As is the case with all opioid medication, the opioids ceased to be effective after a period of time and my doctor titrated the dose up. I finally got the point where I could not tolerate the medication. It was like taking and all day stupid pill. I stopped both cold turkey. Let me tell you, the Oxycontin was by far the worst of the two. The withdrawal from the MSContin wasn't fun but the Oxycontin was orders of magnitude worse.I had a period of severe Myoclonic shocks (what some people call 'brain zaps')during my withdrawal from the pain medication. So severe that they put me on Klonopin for a week. If you ever get treated for pain DO NOT take this medication for more than 2 weeks!
Oxycontin is THE most dangerous drug every conceived by man.
The week I went through withdrawal was the worst seven days of my life. After I got off of it I told my doctor NEVER to prescribe these for me again unless I was dying of cancer and I had him put it in my medical record.
My doctor subsequently recommended that I get into Pain Management (again) and the doctors that I had consultations with recommended that I try Cymbalta for the pain and associated depression. I have been taking the medication for 4 days now and I have noticed that it makes me tired at the end of the day. Not a run down feeling, just TIRED, and I have the yawns after about 5:00 PM. I actually am sleeping much better than I have been for many, many months.
I have noted no other side effects.
It has improved my mood (my wife has noticed this already) however I still have to fight that morning battle to get up and get moving. I have not noticed any significant effect on my back pain, however the doctors indicted it would take several weeks to become effective (like all anti-depressants).
After reading some of the posts here, I am wondering if starting Cymbalta was a major mistake.
I have taken and stopped SSRI's in the past, with no adverse effects, or what you could classify as withdrawal symptoms.
I read the Cymbalta medication information slip carefully and it does NOT indicate that Cymbalta can be so ferociously addictive.
I have been reading some horror stories online and it's making me nervous.
Can anyone offer any advice?
Nervous
#15
Posted 17 January 2008 - 11:41 PM
#16
Posted 18 January 2008 - 12:10 AM
I don't know which end is up. The doc had me start Zoloft and stop the Cymbalta. I had taken Zoloft with no problems 12 years ago. First couple of days I just had roaring headaches in the afternoon thne I started to feel nausea the next 2 days and last night I was really, really sick and had bone pain ALL over-like Flu, but without fever. I caved in this morning and stayed home. I am finally not nauseous any more and the pain is much less, but I keeping staggering and my joints don't seem to be working right. I bet I will never know whether this is the Cymbalta, a virus or the Scleroderma. My money is on the Cymbalta though-I do think that it should be avoided. All of the SSRI's etc. have some side effects-everyone reacts differently-but proceed with caution-ask LOTS of questions and don't be bullied into taking anything you don't trust.
#17
Posted 18 January 2008 - 06:05 PM
I have no doubts about "making it," having had prior experience successfully kicking some highly addictive substances. If quitting something makes you sick, then that something is addictive, according to my way of thinking. All the rest is in the mind I say.
Since I last wrote, I have reduced the Cymbalta dose to 5mg/day and, after three days more, quit altogether. Physiological discomfort today is not much worse on none than it was on 5mg, and I find that 25mg of Benedryl twice a day does a lot to reduce the transient weird sensations. I believe it may take months for this drama to play out.
I am experiencing no emotional problems I can relate to having quit. I'm definitely unused to having such perceived increased energy since quitting, but that's no problem as long as I manage it prudently. My wife says I'm getting my sense of humor back!
My ADD is slightly more problematic though I can't really attribute that to the absence of Cymbalta. I'm a little spacier than usual. For adult ADD, I've been on 60mg of Strattera daily for about 6 months now, somewhat under the lowest recommended effective daily dose, but I think it's a bad idea to make multiple drug dose changes simultaneously, as that makes it really difficult to tell what's doing what.
As a stroke victim (2004), keeping my blood pressure under control takes precedence over most all other healthcare concerns. My biggest surprise here so far is that Cymbalta raised my blood pressure a whole lot. I'd been under the impression that Cymbalta wouldn't do that. Now I use less than half the lisinopril I'd had to take daily to control the hypertension problem caused, I'd thought, only by Strattera.
So far, intestinal gas is the biggest problem I've had with quitting Cymbalta. I am beginning to suspect that what we all have been referring to as brain zaps may have something to do with gas and nothing more.
P.S. Oh PLEASE, folks: the word is spelled W-E-A-N :!: Thx.
#18
Posted 18 January 2008 - 11:56 PM
BTW, in response to one post above, I have had some serious fibromyalgia for around 30 years, and for a long time I used prescription Naprosyn for symptomatic relief although Naprosyn did my stomach no favors. Some 10 years ago I replaced that with Voltaren (diclofenac) which instead has almost no side effects and seems much more effective. The idea that a doctor would prescribe Cymbalta to someone for what is essentially a chronic connective tissue disorder seems just plain weird to me. :roll: But what do I know? Usually less than I think, but my hunches are often pretty good.
#19
Posted 04 February 2008 - 09:12 PM
#20
Posted 05 February 2008 - 02:14 PM
Starting yesterday, I'm back down to what I think is about 5mg/day of Cymbalta. That's 45 or so of the little granules contained in a 20mg capsule. I expect to feel the dastardly results of this reduction in a few days, but you gotta do what you gotta do, as they say. This is the last step before I quit altogether, and I plan to stay at this level for at least a month. I'll provide feedback as time goes on.
For the past several weeks I've been taking my dose around 7 PM instead of in the morning. I sleep pretty well and can get through the next workday without noticeable problems. Emotionally, I have been getting extremely grouchy toward the end of the afternoons, but it seems to wear off by 9PM. Don't know how much of that mood swing is due to taking my dose and having dinner, and how much is just getting to be a grumpy old man... 8-)
To Hopeless Feeling-- You sure have a complicated situation. It's so hard to identify what is causing what. We all are victims of the pharma industry's greed and our own lack of sophistication in such matters. Our doctors are overworked and underinformed as well. I don't understand your dose level. I've thought Cymbalta comes in 60, 40, and 20 mg, so how do you have a dose of 30mg? In any case, please get, read and follow Dr Glenmullen's book for good guidance in getting off this stuff. Really!
#23
Posted 06 February 2008 - 09:01 PM
Angie
#24
Posted 07 February 2008 - 12:53 PM
Welcome aboard. My previous posts here detail my own experience trying to quit from 60mg. At the moment I'm down to 5mg/day and am in the first week of physical and emotional unpleasantness resulting from a reduction from 10mg/day. Cymbalta is a dangerous chemical, and caution and patience are very necessary. I found Dr Glenmullen's book very revealing of the situation I find myself in, and you can find it at addall.com. Good luck, and please stay in touch! 8-)
#25
Posted 19 February 2008 - 07:59 AM
#26
Posted 19 February 2008 - 03:29 PM
I'm glad you started this site!
I've been treated for depression for years. Last year< I found I have hypothyroidism and one of the symptoms is depression. Had my psychiatrist every tested me for thyroid problems? Nope! Found a holistic MD guiding me through withdrawing from Cymbalta-60 mg/day that I've been taking for the last 2 years. I've been dissolvong cap contents into 8 ounces of water and drinking one less ounce per week (down to 4 ounces of 30 mg.). I'm making the move to St. John's wort and 5 HTP for the time being. Depressed right now but could be the holiday season, too. I'm off work til next week and it's gloomy out.
Anyone try SJW and 5HTP?
What an interesting approach! I never would have thought of dissolving and drinking one less ounce per week! I may try that! I used to take SJW, and it worked very well for me for mild to moderate depression. It can cause sun sensitivity, but hey, compared to brain zaps, that's a piece of cake. Also, I had to stop taking it for other reasons at the time, and yep, cold turkey, no problems!! I do know that you should not take SJW with other antis, but if you are working with a holistic doc, I'm sure you are both aware of this. Once this poison is out of my system, I'm going to try SJW again.
#29
Posted 21 February 2008 - 03:26 AM
I'm still on 5 mg/day of cymbalta, taken at 6pm daily. I had thought that the worst effects of the 10 to 5 mg reduction would be changing into a relatively easy period of time after 3 weeks at 5 mg but for me I was wrong. Now I wonder of it is wise for me to reduce to ZERO on March 1 as planned. I'd hoped for a short period of withdrawal symptom relief before the 5-to-none siege begins. I know we're all different, but if anyone's been in my spot, what do you suggest for me now? By mid-afternoon each day I get physically uncomfortable. Want to "jump out of my skin" even. Very touchy emotional feelings too. This gets worse and worse until I finally take my dose at 6pm and all of this fades away until the next day when the cycle repeats. Any ideas appreciated!
#30
Posted 21 February 2008 - 04:25 AM
Post back with what you have decided to do, and good luck. Do try benedryl, it seems to be helping me.
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