Cureus. 2021 Mar 5;13(3):e13715. doi: 10.7759/cureus.13715.
Duloxetine-Induced Liver Injury: A Case Report
Bilal Malik 1, Basel Abdelazeem 1, Taylor Revere 2, Nischit Baral 1, Arvind Kunadi 3
PMID: 33833926 PMCID: PMC8019536 DOI: 10.7759/cureus.13715
Abstract
We present a case of a young (43-year-old), otherwise healthy, female patient who developed drug-induced liver injury (DILI) secondary to routine use of duloxetine. Our case aims to raise awareness amongst physicians about the possibility of duloxetine-induced liver injury. We recommend monitoring liver function tests (LFTs) when initiating or adjusting the dose of duloxetine, and intermittently thereafter, to facilitate early identification and management of potential DILI.
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Note - This report caught me by surpise as this is a well known event and liver function tests have always been recommended since Cymbalta went on the market.
