OK PW
Here is the info I have found so far that would possibly be applicable to your situation/
Member comments
Vinpin,
Regarding seizures, that's a subject I do have personal experience with. The good news is that I'm seizure free for more than 10 years. The bad news is that I had half a dozen gran mal seizures in the 12 years prior, starting with wellbutrin. I tend to believe the seizures all came from the various meds (15-20 combinations) I went through. The only thing that seems to have stopped the seizures is the anti seizure medicine Keppra.
HRTbroken Posted 12 December 2018 - 11:59 AM
she did a month long trial of Wellbutrin, which is a dopamine re-uptake inhibitor to see if it would help with the sexual side effects of being on Cymbalta, but she found it made things worse. That was a year ago though. It may have played a role in this,
I also refer you back to IUN's post
Iknowthiswillgetbetter on 20 September 2020 - 06:02 AM
My doctor once again said he could cross taper me onto Wellbutrin and then I could stop taking the Cymbalta in a week.
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Section of old thread...
I Need Some Help
Posted by Usedtobejoyful on 25 June 2020 - 02:32 PM in Cymbalta Lawsuit Information & News
Oh and I rarely drink anything, not planning on having anything anytime soon I did research all the side effects of Wellbutrin, so I am aware of that. I also kind of had heard about the side effects of going off Cymbalta, but wow. Just wow.
#93905I Need Some Help
Posted by Usedtobejoyful on 25 June 2020 - 02:28 PM in Cymbalta Lawsuit Information & News
Thank you, for the quick responses. I am on the XL Wellbutrin. The doctor said today it is fine for me to continue the 20mg, and do the tapering at my own pace. I am open for any of your suggestions, my doctor (psychiatrist) will work with me on this.
#93902I Need Some Help
Posted by fishinghat on 25 June 2020 - 01:20 PM in Cymbalta Lawsuit Information & News
Here is the situation Joy. It takes Wellbutrin 6 to 8 weeks to kick in so it may still be a little over a monthg before you feel the full effects of the 300 mg Wellbutrin. Also, Wellbutrin controls norepinephrine (similar to adrenaline) and dopamine while Cymbalta controlls norepinephrine and serotonin. The reason I mention this is that once the Wellbutrin fully kicks in you may still have some issues with serotonin balance until your body adjusts. This would include some emotional swings and maybe some GI issues. Hopefully the Wellbutrin will be able to compensate for that but you should be prepared in case.
You can come off the Cymbalta slower than the dr recommended but you would be at risk for seizures. In addition, you should not consider the use of alcohol while on Wellbutrin. Using Wellbutrin with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. On the other hand, sudden withdrawal from alcohol following regular or chronic use can also increase your risk of seizures during treatment with Wellbutrin.
There are some medications your dr can prescribe for any anxiety type symptoms but I hesitate to mention them as they may make the depression worse.
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Posted by Usedtobejoyful on 25 June 2020 - 09:20 AM in Cymbalta Lawsuit Information & News
I am trying to withdraw from this awful medicine. I am transitioning to Wellbutrin (at 300 mg now), from Duluxotine, I was up to 120 mg (60 twice a day). I am down to 20 mg once a day, she went from 60 twice a day to 30 once a day, then she stopped it. OMG I had almost every symptom and it was terrifying, as I am normally a easy-going person, working 3 jobs to a non functioning adult...I called and she put me back on 20 mg a day for 2 weeks then wanted me to do every other day. I am waiting for a call back, because I think I need to go much longer, and maybe even go back up to 30? Then start the whole bead removal process? I have been on it for several years, just increasing from 90 to 120 in January. I am on it for depression (2 suicide attempts, been 9 years since hospitalization for that) I need some help transitioning. advice? I am experiencing most of the symptoms and am having trouble with working, concentrating, functioning, etc.
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Bella407 on 04 May 2020 - 08:06 PM in Question and comments for Me
Good Evening Everyone,
I have been on 90mg Cymbalta for over four years due to depression, it was actually added in conjunction with another medication I take which is 450 mg Wellbutrin.I'm med resistant is why the high doses. I was also put on other medications Seroquel, Topamax when my son died three years ago. I was diagnosed with PTSD 6 months after his death. I meet with my psychiatrist 1x per week for therapy sessions. We discussed taking me off of the Cymbalta and he gave me information on the withdrawal symptoms. He properly tapered me down and I took my last dose on Friday. I'm already having some pretty intense symptoms such as headaches, bad dreams, body aches, anxiety, flashing lights in front of my eyes. My fear is that I may begin to have suicidal thoughts as it's been reported that this is a symptom of the withdrawal. Has anyone experienced this? I'm concerned because I am still grieving my sons death and I may need more support during this time. Any feedback is appreciated.
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Posted by a63548 on 16 June 2019 - 11:11 PM in Weaning Off Cymbalta
I've been taking 120mg Cymbalta daily, along with 300mg Wellbutrin daily, with 1mg of Ativan 1-2 times a day as needed, with Gabapentin to help with anxiety as well. For sleep I'm also prescribed 10mg Ambien, and 30mg Temazepam to alternate between.
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Posted by mforster on 13 April 2019 - 06:16 AM in Weaning Off Cymbalta
I was prescribed 20mg of cymbalta after having bad experiences with both zoloft and wellbutrin. I didn't like the emotional flattening, the fatigue, and the lack of motivation--turned my anxiety into depression!
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Posted by Brijo on 21 February 2019 - 03:39 PM in How to Find Support
The cardiac doc changed his meds from Zoloft to Wellbutrin (summer time). The Wellbutrin also cause side effects oso his GP switched him to Cymbaltoa 20 mg around a month ago.
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Posted by Jgfergie on 23 October 2018 - 11:32 A
Prior to figuring out that it was the Wellbutrin that was causing the anxiety, I started to spread it out to get more coverage.
Posted by redhouse on 16 September 2018 - 06:29 AM
My doctor prescribed Wellbutrin and Buspirone for the anxiety. I have only been on Wellbutrin for 8 days but my anxiety has been even WORSE during that time. Suicidal thoughts, difficulty eating (6 lbs down this week), difficulty sleeping, and unable to engage in life activities. Since it has only been 8 days I am thinking of just stopping it. I don't want to take it today.
Note - This member had quit Cymbalta cold turkey and was goin g through full withdrawal when they made this post.
Posted by popprincess on 02 September 2018 - 12:44 PM
Currently I am on 13mg of Cymbalta (and 200mg of Wellbutrin). After taking Cymbalta 60mg / Wellbutrin 200mg for two years (before that, I had been on some combination of SSRIs and Wellbutrin for the previous 15 years), I began to taper off the Cymbalta for the past year as follows:...
Posted by jltshop on 18 August 2018 - 05:48 PM
I briefly tried Wellbutrin SR 100mg once a day and it caused anxiety, nervousness and palpitations.
Posted by Linda0917 on 13 April 2018 - 02:42 PM
Up until March 20 I was taking a small dose of wellbutrin(1/8 or less of a 75mg tablet) to help with the panic attacks but I wasn't able to eat or sleep on wellbutrin so I needed to get off.
Posted by Linda0917 on 30 March 2018 - 09:01 A
I have been off Cymbalta since January 4 and Wellbutrin for about 2 weeks. I took the 1/8 of a pill and pinched pieces off for several days to wean off. Just when I think it's over the panic attacks start again. I don't remember ever having these before and now I am literally afraid of everything! I have been on my own since I was 12 yrs old. I raised 2 kids on my own, this is not me. It's driving me crazy!
Posted by Cjmansf on 18 March 2018 - 08:10 AM
In the past I had been prescribed Wellbutrin as an add on to Lexapro. The doc thought it would help with the Lexapro side effects. It just ended up making me irritable and such.
Posted by Linda0917 on 13 March 2018 - 06:21
The doctors convinced me to go back on antidepressants so I went on wellbutrin thinking it wouldn't be so hard to get off of forgetting about the side effects of the wellbutrin which is not being able to eat or sleep!!! I'm down to 95 lbs. I actually count calories to gain weight. I'm finally able to control my panic attacks but I'm still not able to deal with the problems causing the anxiety because of the panic attacks. I want to get off the wellbutrin so bad so I can sleep and eat again. I've cut that down very slowly. I tried to stop after dropping down to 1/4 of a tablet and ended up back to the 24/7 panic attacks. I've now cut the tablet into 8 pieces (a feat which is difficult in itself) and have been for about 2 days now. Anybody have any suggestions as to how long I should continue and could I just try to stop or should i attempt to cut it even smaller? I'm just now able to somewhat eat again but only a little at a time. I still can't sleep without over the counter sleep meds and a lorazepam because the doctor won't let me have them much longer and I'm trying so hard not to take but I have to sleep.
Posted by Thomthepainter on 26 February 2018 - 11:15 AM in ARE YOU NEW HERE? Words from the wise about Cymbalta
This is my first post here. Just found it this morning while desperate to find out more about the terrible affects I'm experiencing since abruptly stopping Cymbalta per my Doctors' orders and began taking Wellbutrin in an attempt to lessen or completely getting rid of the sexual side effects ie: erectile dysfunction caused by Cymbalta. I was not told by my doctor about ANY withdrawal effects from doing this.
Posted by Kerro on 24 January 2018 - 02:17 AM in How to Find Support
I'm new here and I'm about 10 days into the hell of withdrawal. I've been on 120mg of Cymbalta for a number of years and gained a huge amount of weight. My new pdoc has been moving me to a new antidepressant (buproprion aka wellbutrin aka zyban) because of the weight issues. He's had me gradually reducing Cymbalta in 30mg chunks while gradually increasing the bupropion since last November and mostly things were going fine until about 10 days ago when I stopped the last of the Cymbalta.
Enter constant headaches, brain zaps, dizziness, nausea, sweating, a high fever, incredible rage at the tiniest thing, and endless tears. Thank you Eli-Lilly. I can't work feeling like this, let alone do much else. I'm trying to keep in touch with work stuff but finding it hard to sit up for more than about 30 mins before the headache and dizziness send me back to bed.
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Drugs.com
Applies to: Wellbutrin (bupropion), Cymbalta (duloxetine)
Talk to your doctor before using buPROPion together with DULoxetine. Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of DULoxetine, which may increase other side effects. You may be more likely to experience seizures with these medications if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma.
Pharmacol Biochem Behav. 2014 Sep;124:238-44. doi: 10.1016/j.pbb.2014.06.005. Epub 2014 Jun 14.
Augmentation of antidepressant effects of duloxetine and bupropion by caffeine in mice.
The objective of the present study was to evaluate the augmentation of antidepressant effects of duloxetine and/or bupropion with caffeine. Comparison between vehicle treated group and other groups showed significant decrease in immobility in all drug treated groups in both antidepressant models. Caffeine plus duloxetine treated group was better among the combination treated groups in terms of decrease in immobility and increase in norepinephrine, dopamine, and serotonin levels in hippocampi, cerebral cortices, and whole brain when compared to their respective monotherapy treated groups. These combination approaches may help in reducing the dose of duloxetine/bupropion, and consequently lower the associated side/adverse effects.
Translation - Caffiene in combination with Cymbalta helps decrease fatique and sluggishness (side effects of Cymbalta). It also increased concentrations of norepinephrine, dopamine and seratonin in the hippocampus, cerebral cortex and the whole brain.
